Categories
Microbiology

How do you define quality for the clinical laboratory?

Learning Goal: I’m working on a microbiology question and need support to help me learn.
The topic of this discussion is quality. Review the material for this week and this article from Medical Lab Management on Quality:
Quality MLM – PDF Document (547 KB)
How do you define quality for the clinical laboratory? What are the various levels of quality? Discuss QMS, QA, QC, PT. Please first discuss the materials. You may include material from other sources, if properly referenced, but it is not acceptable to cut and paste your response.

Categories
Microbiology

Why does a population of microbes not die instantaneously when exposed to an antimicrobial agent?

Learning Goal: I’m working on a microbiology multi-part question and need an explanation and answer to help me learn.
There are 4 essay questions. Please be sure to complete all of them with thorough substantive responses. Citations are required for all responses. There is no time limit.
Precisely what is microbial death?
Why does a population of microbes not die instantaneously when exposed to an antimicrobial agent?
Explain what is wrong with this statement: “Prior to vaccination, the patient’s skin was sterilized with alcohol.” What would be a more correct wording?
Conduct additional research on the use of triclosan and other chemical agents in antimicrobial products today. Develop an opinion on whether this process should continue, providing evidence and citations to support your stance.

Categories
Microbiology

Why do you think patients were tested for antibody to the virus instead of for the presence of the virus itself?

Learning Goal: I’m working on a microbiology discussion question and need an explanation and answer to help me learn.
Hepatitis C is a chronic liver infection that can be either silent (with no noticeable symptoms) or debilitating. Either way, 80% of infected persons experience continuing liver destruction. Chronic hepatitis C infection is the leading cause of liver transplants in the United States. The virus that causes it is blood borne, and therefore patients who undergo frequent procedures involving transfer of blood are particularly susceptible to infection. Kidney dialysis patients belong to this group. In 2008, a for-profit hemodialysis facility in New York was shut down after nine of its patients were confirmed as having become infected with hepatitis C while undergoing hemodialysis treatments there between 2001 and 2008.
When the investigation was conducted in 2008, investigators found that 20 of the facility’s 162 patients had been documented with hepatitis C infection at the time they began their association with the clinic. All the current patients were then offered hepatitis C testing, to determine how many had acquired hepatitis C during the time they were receiving treatment at the clinic. They were considered positive if enzyme-linked immunosorbent assay (ELISA) tests showed the presence of antibodies to the hepatitis C virus.
Health officials did not test the workers at the hemodialysis facility for hepatitis C because they did not view them as likely sources of the nine new infections. Why not?
Why do you think patients were tested for antibody to the virus instead of for the presence of the virus itself?